3.8 Article

The TNA-family of nucleic acid systems: Properties and prospects

Journal

ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE
Volume 34, Issue 3, Pages 277-306

Publisher

KLUWER ACADEMIC PUBL
DOI: 10.1023/B:ORIG.0000016450.59665.f4

Keywords

C-nucleosidation; etiology of nucleic acid structure; origin of life; prebiotic chemistry; threofuranosyl nucleic acids

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This report summarizes the content of the author's lecture given at the 9th ISSOL Conference on the 'Origin of Life' in Oaxaca on 2 July 2002. The report consists of introductory remarks followed by a reproduction of the authentic sequence of slides shown during the lecture. Each slide figure is accompanied with a short commentary on the figure's content. The lecture dealt with the structure and the properties of TNA (alpha-threofuranosyl nucleic acid) and included results of some more recent chemical investigations that had been inspired by the simplicity of TNA's molecular architecture.

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