Journal
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Volume 21, Issue 6, Pages 725-735Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/07391102.2004.10506963
Keywords
energy functions; quality features; protein decoy sets
Categories
Ask authors/readers for more resources
Energy functions are crucial ingredients of protein tertiary structure prediction methods. Assessing the quality of energy functions is therefore of prime importance. It requires the elaboration of a standard evaluation scheme, whose key elements are: i) sets that contain the native and several non-native structures of proteins (decoys) in order to test whether the energy functions display the expected quality features and ii) measures to evaluate the reliability of energy functions. We present here a survey of the recent advances in these two related fields. In a first part, we analyze and review the large number of decoy sets that are available on the web, and we summarize the characteristics of a challenging decoy set. We then discuss how to define the quality of energy functions and review the measures related to it.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available