Application of thin film mercury electrodes and solid amalgam electrodes in electrochemical analysis of the nucleic acids components: detection of the two-dimensional phase transients of adenosine

The optical diffractive (DOE)-based sensor was used to the study of the optical roughness of different carbon/graphite electrodes modified by mercury film (MFEs) and solid amalgam-alloy electrodes (S-MeA-Es). The electrode surfaces were visualised by an optical metallurgical microscope. The adsorption of adenosine at the MFEs and S-MeAEs has been investigated by capacitance measurement. Some kinetics aspects, such as the influence of the surface morphology, nature of the substrate and thickness of the mercury film and amalgam-alloy on the formation of two-dimensional (2D) physisorbed adenosine adlayer on the MFEs and S-MeAEs, were studied. (C) 2004 Elsevier B.V. All rights reserved.