Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 4, Issue 5, Pages 487-492Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557043403828
Keywords
ribosome inactivating protein; ricin; pokeweed antiviral protein; RNA N-glycosidase
Categories
Ask authors/readers for more resources
Ribosome-inactivating proteins (RIPs) are a heterogeneous group of enzymes found mainly in plants and a few bacteria that possess N-glycosidase activity on ribosomes and a related polynucleotide adenosine glycosidase activity on naked nucleic acids. They encompass single enzymatic chains, heterodimeric toxic lectins and related agglutinins. Plants commonly produce several RIP isoforms encoded by multi-gene families. The toxic lectins possess adaptations related to their cytotoxic role.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available