Journal
CANADIAN JOURNAL OF GASTROENTEROLOGY
Volume 18, Issue 6, Pages 397-399Publisher
PULSUS GROUP INC
DOI: 10.1155/2004/360537
Keywords
botulinum toxin A; dysphagia; inclusion body myositis
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Inclusion body myositis (IBM) is a progressive degenerative skeletal muscle disease leading, to weakening and atrophy of both proximal and distal muscles. Dysphagia is reported in up to 86% of IBM patients. Surgical cricopharyngeal myotomy may be effective for cricopharyngeal dysphagia and there is one published report that botulinum toxin A, injected into the cricopharyngeus muscle using a hypopharyngoscope under general anesthesia, relieved IBM-associated dysphagia. This report presents the first documentation of botulinum toxin A injection into the upper esophageal sphincter using a flexible esophagogastroduodenoscope under conscious sedation, to reduce upper esophageal sphincter pressure and successfully alleviate oropharyngeal dysphagia in two IBM patients.
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