Folate and vitamin B12 recommended intakes and status in the United States

This paper presents a synopsis of the Institute of Medicine (IOM) Dietary Reference Intakes (DRIs) for folate and the recommended folic acid intake to reduce the risk of neural tube defects. Estimated intake of folic acid is presented and total folate intake is compared to the DRI. Vitamin B-12 DRIs are highlighted in addition to the IOM recommendation for crystalline vitamin B-12 intake specifically for individuals >= 51 years of age. Recently reported evidence of vitamin B-12 inadequacy in the aging segment of the U.S. population will be addressed.