Journal
TRENDS IN PHARMACOLOGICAL SCIENCES
Volume 25, Issue 6, Pages 306-310Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tips.2004.04.002
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The dramatic increase in both the number of novel infectious agents and resistance to antimicrobial drugs has incited the need for adjunct therapies in the war against infectious diseases. Exciting recent studies have demonstrated the use of antibodies in the form of intravenous immunoglobulin (IVIg) against infections. By virtue of the diverse repertoire of immunoglobulins that possess a wide spectrum of antibacterial and antiviral specificities, Wig provides antimicrobial efficacy independently of pathogen resistance and represents a promising alternative strategy for the treatment of diseases for which a specific therapy is not yet available.
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