Coordination chemistry of 1,3,5-triaza-7-phosphaadamantane (PTA) - Transition metal complexes and related catalytic, medicinal and photoluminescent applications

The cage-like water-soluble monodentate phosphine 1,3,5-triaza-7-phosphaadamantane (PTA) has received renewed interest in the recent literature due to its properties to solubilize transition metal complexes in aqueous phase. This property has allowed application of Rh, Ru and Pd-PTA complexes in aqueous phase or biphasic homogeneous catalysis, antitumoral tests (Ru- and Pt-PTA) and photoluminescence (Au-PTA). This paper reviews the synthesis and structural properties of PTA and derivatives, their transition metal complexes, catalytic, medicinal and photoluminescence uses. (C) 2004 Elsevier B.V. All rights reserved.