Journal
TRENDS IN PARASITOLOGY
Volume 20, Issue 6, Pages 262-265Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2004.03.008
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The analysis of unique longitudinal data of Plasmodium parasites in Papua New Guinean children led to the postulation that a nonspecific density-dependent mechanism is generally implicated in regulating the parasite load. The necessity to postulate such a mechanism given the acknowledged species- and strain-specificity of antimalarial immunity is discussed through a critical assessment of these data and the hypothesis.
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