Journal
NATURE REVIEWS CANCER
Volume 4, Issue 6, Pages 457-469Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc1368
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Positron-emission tomography (PET) is a powerful tool for imaging and quantifying cellular and molecular processes in humans. It has enormous potential to increase our understanding of the pathophysiology of human tumours and to support the development of anticancer drugs. The ability of PET to image mechanisms of anticancer-drug resistance in vivo should be exploited in proof-of-concept studies at early stages of drug development.
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