Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 101, Issue 1-2, Pages 150-154Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2004.02.057
Keywords
immumosensor; quartz crystal microbalance (QCM); fibrinogen and fibrin degradation products (FDP); immunized latex; smart QCM-sensor
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We have developed a rapid immunosensor for fibrinogen and fibrin degradation products (FDP) that combines a quartz crystal microbalance (QCM) with the agglutination reaction of anti-FDP antibody immunized latex beads. We measured FDP concentration successfully in human serum within 10 min with a smart QCM-sensor. The detection range of the smart QCM-sensor is covered with screening concentration of FDP in serum (less than 10 mug ml(-1) of FDP). (C) 2004 Elsevier B.V. All rights reserved.
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