Study of antioxidant properties of a water-soluble vitamin E derivative - tocopherol monoglucoside (TMG) by differential pulse voltammetry

Study of antioxidant properties of tocopherol monoglucoside (TMG), a water-soluble Vitamin E derivative, by differential pulse voltammetry has been carried out in this work. The pH influence on the antioxidant properties of TMG has been also investigated. It was observed that the antioxidant activity of TMG is greater at 6.90 < pH < 9.18. The reactions between the TMG and reactive oxygen species have been considered. Antioxidant activity of some standard antioxidants including Vitamin E was given for comparison. The results indicate that the TMG is an effective antioxidant in neutral solutions. The oxidation potential for TMG at pH 7.31 has been found (E = 0.55 +/- 0.03 V versus Ag\AgCl\KClsat electrode). Finally the use of TMG for protection against oxidative stress has been recommended. (C) 2004 Elsevier B.V. All rights reserved.