4.5 Article

First total synthesis of structurally unique flavonoids and their strong anti-inflammatory effect

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 14, Issue 12, Pages 3201-3203

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2004.03.108

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The first total synthesis of structurally unique flavonoids 1alpha and 1beta is described. These compounds showed very strong anti-inflammatory effect against delayed hypersensitivity in a mouse model. (C) 2004 Elsevier Ltd. All rights reserved.

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