4.5 Article

A new approach to the synthesis of optically active alkylated adenine derivatives

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 14, Issue 12, Pages 3357-3360

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2003.12.107

Keywords

acyclic nucleosides and nucleotides; synthesis

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A new synthesis of chiral acyclic nucleoside and nucleotide analogues starting from D(-)- or L(+)-riboses was proposed. Antiviral properties of the synthesized compounds towards the pox virus family were evaluated. (C) 2004 Elsevier Ltd. All rights reserved.

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