Journal
ORGANIC LETTERS
Volume 6, Issue 13, Pages 2257-2260Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol049267j
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- NCI NIH HHS [CA34619] Funding Source: Medline
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[GRAPHICS] A novel method for the preparation of nucleoside triphosphates has been developed. The strategy employs a highly reactive pyrrolidinium phosphoramidate zwitterion intermediate that undergoes efficient coupling with tris(tetra-n-butylammonium) hydrogen pyrophosphate to generate nucleoside triphosphate.
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