Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2004, Issue 13, Pages 2763-2772Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200400003
Keywords
Mitsunobu reaction; fluorous compounds; phosphanes; azo compounds; phase switching
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Recent progress in synthetic approaches to the Mitsunobu reaction are reviewed. Efforts that have focused on the phase-switching modifications of phosphane, azodicarboxylate, and nucleophilic components are emphasized. An approach to product separation with fluorous compounds is reviewed in detail. Alternative reagents and recently introduced products are cited. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
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