Journal
MAGNETIC RESONANCE IMAGING
Volume 22, Issue 6, Pages 827-833Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mri.2003.12.003
Keywords
fMRI; spatial ICA; localization; brain functional imaging
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By measuring the changes of magnetic resonance signals during a stimulation, the functional magnetic resonance imaging (fMRI) is able to localize the neural activation in the brain. In this report, we discuss the fMRI application of the spatial independent component analysis (spatial ICA), which maximizes statistical independence over spatial images. Included simulations show the possibility of the spatial ICA on discriminating asynchronous activations or different response patterns in an fMRI data set. An in vivo visual stimulation fMRI test was conducted, and the result shows a proper sum of the separated components as the final image is better than a single component, using fMRI data analysis by spatial ICA. Our result means that spatial ICA is a useful toot for the detection of different response activations and suggests that a proper sum of the separated independent components should be used for the imaging result of fMRI data processing. (C) 2004 Elsevier Inc. All rights reserved.
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