Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 32, Issue 3, Pages 112-119Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00003677-200407000-00007
Keywords
myocyte; Ca2+ sensitivity; power output; microarray; atrial myosin light chain
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Recent work suggests that chronic exercise induces alterations in the contractile properties of cardiac myocytes. These alterations include increased sensitivity to activation by Ca2+, changes in the force-length relationship, and increased power output. A recently observed shift in expression of myosin light chain 1 subunit isoforms induced by training may provide a molecular mechanism for these contractile alterations.
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