Journal
NEUROPSYCHOLOGY
Volume 18, Issue 3, Pages 537-542Publisher
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/0894-4105.18.3.537
Keywords
-
Categories
Ask authors/readers for more resources
The aim of this study was to investigate magnocellular (M) and parvocellular (P) visual functions in nonmedicated patients with schizophrenia and in their unaffected siblings. Possible abnormalities in cortical integration of retinal receptive fields also were addressed. Twenty-two nonmedicated patients with schizophrenia, their unaffected siblings, and 20 age- and IQ-matched healthy control subjects received 4 Vernier acuity tasks (blue-on-yellow, frequency-doubling, achromatic low and high contrast conditions) in which they were asked to detect the spatial alignment of dots and gratings. Results revealed that the patients with schizophrenia and their unaffected siblings showed selective dysfunctions in the frequency-doubling and achromatic low contrast conditions, which were devoted to investigate M pathways. In the isoluminant blue-on-yellow and high contrast achromatic conditions, there were no significant differences between the experimental groups. These results suggest that the deficit of M pathway is an endophenotype of schizophrenia.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available