Journal
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Volume 34, Issue 7, Pages 673-678Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.ibmb.2004.03.020
Keywords
Anopheles; Aedes; Plasmodium; mosquito immune response; antimicrobial peptides; hemocytes
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Transmission of human malaria requires a successful development of Plasmodium parasites in anopheline mosquitoes. Insects have developed efficient immune responses to oppose microbial and eukaryotic invaders. The completion of the sequencing of the Anopheles genome provides a wealth of information on putative immune genes that are homologous to components of the Drosophila and mammalian immune systems. In this review, we will summarize our present knowledge of immune responses in the mosquito Anopheles gambiae and attempt a comparative analysis of insect immune systems. (C) 2004 Elsevier Ltd. All rights reserved.
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