Journal
NATURE REVIEWS CANCER
Volume 4, Issue 7, Pages 540-550Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc1388
Keywords
-
Categories
Ask authors/readers for more resources
A complex network of chemokines and their receptors influences the development of primary tumours and metastases. New information about the biological role of chemokines in these processes is providing insights into host - tumour interactions, such as the role of the leukocyte infiltrate, and into the mechanisms that determine the metastatic potential and site-specific spread of cancer cells. Chemokine-receptor antagonists are showing promise in animal models of inflammation and autoimmune disease. Could manipulating the local chemokine network have therapeutic benefits in malignant disease?
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available