4.6 Article

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 7, Pages 1059-1066

Publisher

WILEY
DOI: 10.1359/JBMR.040305

Keywords

RANKL; osteoprotegerin; osteoporosis; bone resorption; AMG 162

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The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to RANKL, was investigated in 49 postmenopausal women. AMG 162 is a potent antiresorptive agent for diseases such as osteoporosis.

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