Journal
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Volume 27, Issue 7, Pages 1144-1146Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/bpb.27.1144
Keywords
Angelica dahurica; tyrosinase inhibition; 9-hydroxy-4-methoxypsoralen; LC/MS
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An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsoralen.
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