Journal
BIOMACROMOLECULES
Volume 5, Issue 4, Pages 1141-1154Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm034513k
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Novel polyisobutylene-based thermoplastic elastomers are introduced as prospective implant materials for soft tissue replacement and reconstruction. In comparison, poly(ethylene terephthalate) (PET), poly(tetrafluoroethylene) (PTFE), polypropylene (PP), polyurethanes (PU), and silicones are outlined from well-established implant history as being relatively inert and biocompatible biomaterials for soft tissue replacement, especially in vascular grafts and breast implants. Some general considerations for the design and development of polymers for soft tissue replacement are reviewed from the viewpoint of material science and engineenng, with special attention to synthetic materials used in vascular grafts and breast implants.
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