4.6 Article

Characterization of a novel bipotent hematopoietic progenitor population in normal and osteopetrotic mice

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 7, Pages 1137-1143

Publisher

WILEY
DOI: 10.1359/JBMR.040318

Keywords

osteopetrosis; osteoclast; hematopoiesis; bone marrow; B-cell differentiation

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Several reports indicate that osteoclasts and B-lymphocytes share a common progenitor. This study focuses on the characterization of this bipotent progenitor from the bone marrow of the osteopetrotic oc/oc mouse, where the bipotent-progenitor population is amplified, and of normal mice.

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