Journal
JOURNAL OF BACTERIOLOGY
Volume 186, Issue 14, Pages 4808-4812Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.186.14.4808-4812.2004
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Enterococcus faecalis and Enterococcus faecium infections are increasingly difficult to treat due to high levels of resistance to antibiotics. PlyV12, a bacteriophage lytic enzyme, was isolated and shown to effectively kill both E. faecalis and E. faecium (including vancomycin-resistant strains), as well as other human pathogens. We propose its development and use as an alternative therapeutic tool.
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