Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 7, Pages 1067-1074Publisher
WILEY
DOI: 10.1359/JBMR.040313
Keywords
osteoporosis; bone densitometry; bone turnover markers; bisphosphonates; spinal cord injury
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To assess the effects of long-term treatment of bone loss with alendronate in a group of paraplegic men, 55 patients were evaluated in a prospective randomized controlled open label study that was 2 years in duration comparing alendronate and calcium with calcium alone. Bone loss was stopped at all cortical and trabecular infralesional sites (distal tibial epiphysis, tibial diaphysis, total hip) with alendronate 10 mg daily.
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