Journal
APPLIED SURFACE SCIENCE
Volume 257, Issue 6, Pages 2346-2352Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2010.09.101
Keywords
Aluminosilicates; Nanostructured microparticles; Protein adsorption; XPS
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Funding
- CNCSIS Romania [PN II IDEI - PCCE 312/2008]
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X-ray photoelectron spectroscopy (XPS) was used to study the interaction of two different sized proteins, bovine serum albumin (BSA) and fibrinogen, with an aluminosilicate system containing yttrium and iron that is a potential biomaterial. Serum albumin and fibrinogen are two major plasma proteins and the most relevant proteins adsorbed on the surface of biomaterials in blood contact. The aluminosilicate samples were incubated for several exposure times, up to 24 h, in simulated body fluid enriched with BSA, and in buffered fibrinogen solution. Time dependence of proteins adsorption onto surface of the investigated samples is reflected by the evolution of the new N 1s photoelectron peak and by the modification of C 1s core-level spectra recorded from the samples immersed in protein solution. (C) 2010 Elsevier B.V. All rights reserved.
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