Journal
APPLIED SURFACE SCIENCE
Volume 257, Issue 6, Pages 2046-2050Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2010.08.128
Keywords
Laser ablation; Nanoparticles; Colloids; Electrophoresis; Surface assisted laser desorption/ionization; SALDI; Mass spectrometry
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Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [470, 21020027]
- Network Joint Research Center for Materials and Devices (Institute for Materials Chemistry and Engineering, Kyushu University)
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Substrates for the surface-assisted laser desorption ionization (SALDI) technique were prepared using electrophoresis of gold nanoparticles produced by laser ablation in liquids. Throughout the preparation, no supplemental reagent was added for the stabilization and deposition of nanoparticles. Nanoparticles were deposited more uniformly using the electrophoresis technique than using dropping of the solution. Results demonstrated that the higher uniformity of the deposition of nanoparticles improved the reproducibility of SALDI measurements. Furthermore, the thickness of the deposited nanoparticles influences the SALDI efficiency. (C) 2010 Elsevier B.V. All rights reserved.
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