Journal
SYNLETT
Volume -, Issue 9, Pages 1637-1639Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2004-829097
Keywords
Kinugasa reaction; beta-lactams; isoxazoline; amino acids; proline
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Synthetically important 3-exomethylene beta-lactams 4a-f were obtained in a single step via Cu(I)-mediated cycloaddition between propargyl alcohol/butyn-2-ol and nitrones 2a-d, in the presence of L-proline (Kinugasa reaction).
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