4.5 Article Proceedings Paper

Complicated electrical activities in cardiac tissue

Journal

INTERNATIONAL JOURNAL OF MODERN PHYSICS B
Volume 18, Issue 17-19, Pages 2645-2650

Publisher

WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S0217979204025841

Keywords

conduction block; fibrillation; spiral wave

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It has become widely accepted that ventricular fibrillation, the most dangerous cardiac arrhythmias, is a major cause of death in the industrialized world. Alternans and conduction block have recently been related to the progression from ventricular tachycardia to ventricular fibrillation. From the point of view in cellular electrophysiology, ventricular tachycardia is the formation of reentrant wave in cardiac tissue. And ventricular fibrillation arises from subsequent breakdown of reentrant wave into multiple drifting and meandering spiral waves. In this paper, we numerically study pulse and vortex dynamics in cardiac tissue. Our numerical results include 1:1 normal sinus rhythm, 2:1 conduction block, complete conduction block, spiral wave, and spiral breakup. All of our numerical findings can be corresponding to clinical measurements in electrocardiogram. Various electrical activities in cardiac tissue will be discussed in detail in the present manuscript.

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