Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1044, Issue 1-2, Pages 131-144Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2004.04.072
Keywords
reviews; electrochromatography; mass spectrometry; interfaces; CEC-MS
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This review discusses the development of capillary electrochromatography (CEC) coupled to mass spectrometric (MS) detection over the last few years. Major topics addressed are instrumental setups employed and applications of this technology published in the recent literature. The instrumental section includes a discussion of the most commonly used interfaces for the hyphenation of CEC and MS as well as ionization techniques. Applications reviewed in this paper come from a variety of different fields such as the analysis of biomolecules like proteins, peptides, amino acids or carbohydrates, chiral separations or the analysis of pharmaceutical an their metabolites in a series of matrices. (C) 2004 Elsevier B.V. All rights reserved.
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