Journal
MOLECULES
Volume 9, Issue 8, Pages 658-665Publisher
MDPI
DOI: 10.3390/90800658
Keywords
Knoevenagel condensation; E-stilbenes; coumarins; potassium phosphate
Ask authors/readers for more resources
Knoevenagel condensations between aldehydes and substrates containing active methylene groups were carried out in ethanol at room temperature, in the presence of potassium phosphate, to afford unsymmetrical olefins. These condensations have been shown to afford only the E-isomers in greater than 80% yields. Salicylaldehyde first produces the Knoevenagel condensation products, which undergo a subsequent heterocyclization to give coumarin derivatives. The structures of the synthesized compounds were established on the basis of UV, IR, MS and NMR spectroscopy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available