4.1 Article

Anaphylaxis with associated fibrinolysis, reversed with tranexamic acid and demonstrated by thrombelastography

Journal

ANAESTHESIA AND INTENSIVE CARE
Volume 32, Issue 4, Pages 580-587

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.1177/0310057X0403200419

Keywords

anaphylaxis; anaphylactoid reactions : fibrinolysis; thrombelastography; mast cells

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In the surgical setting, fibrinolysis can be a serious complication of anaphylaxis. We present four cases of anaphylaxis that were associated with fibrinolysis during anaesthesia, and the use of the thrombelastograph to demonstrate this haemostatic defect and its correction using tranexamic acid.

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