Nematicidal, insecticidal, antifertility, antifungal and antibacterial activities of salicylanilide sulphathiazole and its manganese, silicon and tin complexes

A facile synthesis and studies on. the stereochemistry and biochemical aspects of some olganosilicon(IV), olganotin(IV), and manganese(II) complexes derived from, imine having (NNO)-N-boolean AND-O-boolean AND donor system is reported. The inane teas prepared by the condensation of salicylanilide with sulphathiazole. This imine reacts with olganosilicon(IV)chloride, olganotin(IV)chloride, and hydrated manganese(II) chloride to yield compounds having M-O anal M <-- N bonds. The structures of the compounds have been elucidated by physicochemical anal spectral (IR, H-1 NMR, C-13 NMR, Si-29 NMR, (119) Sn NMR, and ESP) studies, which clearly point to a trigonal bipyramidal geometry around silicon(IV) and tin(IV), and tetrahedral geometry around manganese(II), as the active lone pair of the nitrogen. is also included in. the coordination sphere. In the search for better fungicides and bactericides, studies were conducted. to assess the growth-inhibiting potential of the synthesized complexes against various pathogenic fungal and bacterial strains. These complexes are highly active against nematode (Meloidogyne incognita) and insect (Trogoderma granarium). The activity will be increased with increasing concentration. These studies demonstrate that the concentrations reached levels that ire sufficient to inhibit and kill the pathogens. All, compounds have also been, found to act, as sterilizing agents by reducing the production of sperm in male mice.