4.2 Article

Rapid reversal of global left ventricular dysfunction after accidental injection of 0.75 mg epinephrine in a 20-year-old patient

Journal

ACTA ANAESTHESIOLOGICA SCANDINAVICA
Volume 48, Issue 7, Pages 914-916

Publisher

WILEY
DOI: 10.1111/j.0001-5172.2004.00428.x

Keywords

catecholamines; coronary vasospasm; epinephrine; myocardial stunning; ventricular dysfunction

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We report an accidental injection of epinephrine before spinal anaesthesia in a 20-year-old patient who subsequentely developed immediate myocardial ischemia and global left ventricular dysfunction (ejection fraction of 20%). Hemodynamic status dramatically improved after nitroglycerin, calcium antagonists, acetyl salicylic acid and unfractionated heparin injections. Over 24 h, patient's ejection fraction fully recovered without kinetic abnormality.

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