Journal
JOURNAL OF NATURAL PRODUCTS
Volume 67, Issue 8, Pages 1400-1402Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np049970g
Keywords
-
Ask authors/readers for more resources
During the course of our screening program designed to discover novel anticancer and anti-infective agents from marine microorganisms, a strain of Streptomyces aureoverticillatus (NPS001583) isolated from a marine sediment was found to produce a novel macrocyclic lactam with cytotoxicity against various tumor cell lines. Using extensive MS, UV, and NMR spectral analyses, the structure has been established as compound 1, aureoverticillactam, a 22-atom macrocyclic lactam incorporating both triene and tetraene conjugated olefins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available