Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 379, Issue 7-8, Pages 913-919Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-004-2706-y
Keywords
quantum dots; luminescent nanocrystals; fluorescence; bioanalysis; fluorescent immunoassays
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Luminescent semiconductor nanocrystals, so called quantum dots (QD), have attracted increasing interest for bioanalytical labeling applications in recent years. This review describes the major optical and (bio)chemical features of this class of label, compared with organic dyes. Different conjugation methods are also discussed and the most important recent applications are presented. An overview over the current state-of-the-art is given, as also is an outlook on possibilities and limitations.
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