Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 29, Issue 8, Pages 396-399Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2004.06.002
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We describe GIFT [for GldG, intraflagellar transport (IFT)] domains in the flavobacterial gliding protein GldG and eukaryotic IFT-52. In eukaryotes, domain homologues are also found in the eukaryotic oligosaccharyltransferase complex and in subtilisin kexin isozyme-1 (SKI-1 or S1P). A distant evolutionary relationship to periplasmic-binding proteins hints that GIFT domains might possess oligosaccharide-binding functions.
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