Journal
APPLIED SPECTROSCOPY REVIEWS
Volume 46, Issue 3, Pages 222-241Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/05704928.2011.557121
Keywords
7-Chloro-4-nitrobenzoxadiazole (NBD-Cl); fluorogenic; chromogenic spectrophotometry; spectrofluorimetry; pharmaceutical amines
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Many papers have been presented in recent years regarding the field of application of 7-chloro-4-nitrobenzoxadiazole (NBD-Cl) as a fluorogenic and chromogenic reagent for the determination of pharmaceutical amines using spectrophotometry and spectrofluorimetry techniques. In this review article, various spectrophotometric and spectrofluorimetric methods using NBD-Cl as a labeling reagent for determination of pharmaceutical amines are covered. The application of these methods for the determination of drugs in pharmaceutical and real samples is also discussed.
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