Journal
APPLIED SPECTROSCOPY REVIEWS
Volume 46, Issue 2, Pages 166-173Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/05704928.2010.537005
Keywords
Fluorescence correlation spectroscopy (FCS); biological research; single molecular detection; ligand-receptor interactions; genetics
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Fluorescence correlation spectroscopy (FCS) is an important biophysical technique. FCS is currently being used in many areas of biology to solve several scientific problems. Its properties such as detection at the single molecular level, higher sensitivity, and use of lower sample volume make FCS a promising molecular diagnostic tool. The promising applications of FCS extend from DNA kinetics/dynamics studies to the comprehensive understanding of receptor-ligand interactions. In this article, we review various promising biological applications of FCS.
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