Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 16, Issue 4, Pages 494-498Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2004.05.001
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Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.
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