Journal
MOLECULAR BIOLOGY AND EVOLUTION
Volume 21, Issue 8, Pages 1512-1524Publisher
OXFORD UNIV PRESS
DOI: 10.1093/molbev/msh150
Keywords
phylogenetic analyses; tetrapod evolution; lobe-finned fish; coelacanth; lungfish
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The origin of terrapods is a major outstanding issue in vertebrate phylogeny. Each of the three possible principal hypotheses (coelacanth, lungfish, or neither being the sister group of tetrapods) has found support in different sets of data. In an attempt to resolve the controversy, sequences of 44 nuclear genes encoding amino acid residues at 10,404 positions were obtained and analyzed. However, this large set of sequences did not support conclusively one of the three hypotheses. Apparently, the coelacanth, lungfish, and tetrapod lineages diverged within such a short time interval that at this level of analysis, their relationships appear to be an irresolvable trichotomy.
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