Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 14, Issue 4, Pages 328-335Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2004.06.003
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Funding
- NHGRI NIH HHS [NP50 HG02357-01] Funding Source: Medline
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Pseudogenes are considered as genomic fossils: disabled copies of functional genes that were once active in the ancient genome. Recently, whole-genome computational approaches have revealed thousands of pseudogenes in the genomes of the human and other eukaryotes. Identification of these pseudogenes can improve the accuracy of gene annotation. It also offers new insight on the evolutionary history and the stability of the genome as a whole.
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