Journal
APPLIED PHYSICS LETTERS
Volume 85, Issue 5, Pages 846-848Publisher
AMER INST PHYSICS
DOI: 10.1063/1.1777820
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In medical optoacoustics (photoacoustics), absorbing structures, such as blood vessels, hidden inside scattering media are illuminated with short laser pulses resulting in the generation of thermoelastic pressure transients. This initial three-dimensional (3D) acoustic pressure distribution, which exactly resembles the absorption distribution, was imaged into a water container with a 4f acoustic lens system. An optical dark-field stereo imaging system using a 30 ns flash illumination light was used to capture a snapshot of the pressure-induced refraction index changes in the water container at a predetermined time after the original laser pulse. The imaging system works at 20 Hz frame rate and was designed toward a theoretical resolution of 50 mum. The proposed method directly provides 3D images of absorbing structures without the need of computational reconstruction algorithms. (C) 2004 American Institute of Physics.
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