4.5 Article

Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 14, Issue 15, Pages 3865-3868

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2004.05.073

Keywords

SERMs; SERAMs; estrogen

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A series of benzoxathiin SERAMs with heteroatom-substituted amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue. (C) 2004 Elsevier Ltd. All rights reserved.

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