4.2 Article

In(OTf)3-catalysed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Journal

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Volume 217, Issue 1-2, Pages 47-50

Publisher

ELSEVIER
DOI: 10.1016/j.molcata.2004.02.025

Keywords

Indium triflate; catalysis; Biginelli reaction; dihydropyrimidinone; three component synthesis

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A variety of aldehydes reacted in one-pot with ethyl or methyl acetoacetate and urea or thiourea in the presence of 2 mol% In(OTf)(3) furnishing the corresponding dihydropyrimidinones or their thio analogues in very good to excellent yields. (C) 2004 Elsevier B.V. All rights reserved.

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