Lithium acetate-catalyzed Michael reaction between trimethylsilyl enolate and α,β-unsaturated carbonyl compound

Lithium acetate-catalyzed Michael reaction between trimethylsilyl enolates and alpha,beta-unsaturated carbonyl compounds in DMF proceeded smoothly to afford the corresponding Michael-adducts in good to high yields. Hindered alpha, beta-unsaturated ketones also behaved as an excellent Michael-acceptor in the above reaction at room temperature.