Journal
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
Volume 51, Issue 4, Pages 625-634Publisher
WILEY-LISS
DOI: 10.1002/art.20533
Keywords
systemic lupus erythematosus; biofeedback; stress management; pain
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Funding
- NCRR NIH HHS [5-M01-RR-00056] Funding Source: Medline
- NHLBI NIH HHS [2-R01-HL-5490005, 5-R01-HL-5490002] Funding Source: Medline
- NIAMS NIH HHS [K24-AR-02213, R01-AR-4658802] Funding Source: Medline
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Objective. To assess the effects of a stress-reduction program on pain, psychological function, and physical function in persons with systemic lupus erythematosus (SLE) who experience pain. Methods. Ninety-two SLE patients were assigned randomly to receive either biofeedback-assisted cognitive-behavioral treatment (BF/CBT), a symptom-monitoring support (SMS) intervention, or usual medical care (UC) alone. Results. BF/CBT participants had significantly greater reductions in pain and psychological dysfunction compared with the SMS group (pain, P = 0.044; psychological functioning, P < 0.001) and the UC group (pain, P = 0.028; psychological functioning, P < 0.001). BF/CBT had significantly greater improvement in perceived physical function compared with UC (P = 0.035), and improvement relative to SMS was marginally significant (P = 0.097). At a 9-month followup evaluation, BF/CBT continued to exhibit relative benefit compared with UC in psychological functioning (P = 0.023). Conclusion. This study supports the utility of a brief stress management program for short-term improvement in pain, psychological function, and perceived physical function among persons with SLE who experience pain.
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