4.4 Article

First application of chiral ionic liquids in asymmetric Baylis-Hillman reaction

Journal

TETRAHEDRON LETTERS
Volume 45, Issue 34, Pages 6425-6428

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.06.134

Keywords

ionic liquids; chirality; Baylis-Hillman reaction; asymmetric synthesis

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The first example of the use of chiral ionic liquids as reaction media in the asymmetric Baylis-Hillman reaction was described using N-alkyl-N-methylephedrinium salts. Good yields and significant enantiomeric excesses were obtained. (C) 2004 Elsevier Ltd. All rights reserved.

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